1-Boc-5-Phenylpyrrolidine-3-carboxylic acid

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For R&D use only.

Catalog NO.：A10575
CAS No. : 885277-76-9
Molecular Formula：C₁₆H₂₁NO₄
Molecular Weight： 291.34

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Product Details

CAS Number	885277-76-9	Appearance
Catalog Number	A10575	MDL Number	MFCD06738845
Molecular Formula	C₁₆H₂₁NO₄	Molecular Weight	291.34
Boiling Point	441.471°C at 760 mmHg	Melting Point
Flash Point		Density
Synonyms	1-Boc-5-Phenylpyrrolidine-3-carboxylic acid
Storage Condition	Store in a tightly closed container,in a cool and dry place

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Description

Tucatinib, also known as Irbinitinib, ARRY-380 and ONT-380, is a n orally bioavailable inhibitor of the human epidermal growth factor receptor tyrosine kinase ErbB-2 (also called HER2) with potential antineoplastic activity. ErbB-2 inhibitor ARRY-380 selectively binds to and inhibits the phosphorylation of ErbB-2, which may prevent the activation of ErbB-2 signal transduction pathways, resulting in growth inhibition and death of ErbB-2-expressing tumor cells. ErbB-2 is overexpressed in a variety of cancers and plays an important role in cellular proliferation and differentiation.

937263-43-9 (Arry-380)

937265-83-3 (ARRY-380 analog)

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