4-Benzyl-2-(chloromethyl)morpholine

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For R&D use only.

Catalog NO.：A6822
CAS No. : 40987-25-5
Molecular Formula：C₁₂H₁₆ClNO
Molecular Weight： 225.71

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Product Details

CAS Number	40987-25-5	Appearance
Catalog Number	A6822	MDL Number	MFCD02681886
Molecular Formula	C₁₂H₁₆ClNO	Molecular Weight	225.71
Boiling Point	314.6℃ at 760 mmHg	Melting Point
Flash Point	144.1℃	Density
Synonyms	4-Benzyl-2-(chloromethyl)morpholine
Storage Condition	Store in a tightly closed container,in a cool and dry place

Safety

GHS Pictogram
Signal Word	Danger	UN Number	1759
Hazard Statements	H314	Class	8
Precautionary Statements	P280-P305+P351+P338-P310	Packing Group	Ⅲ

Description

High affinity allosteric kinesin spindle protein (KSP) inhibitor (Ki app = 1.7 nM). Exhibits >10,000-fold selectivity for KSP over a range of other mitotic kinesins. Inhibits proliferation and induces apoptosis of prostate and breast cancer cells in vitro. Induces tumor regression of breast cancer cell xenografts in mice.

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H200	Explosives (Unstable Explosive)
H201	Explosives （Div 1.1)
H202	Explosives (Div 1.2)
H203	Explosives (Div 1.3)
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H302	Acute toxicity,oral (Category 4)
H303	Acute toxicity,oral (Category 5)
H304	Aspiration hazard (Category 1)
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H312	Acute toxicity,dermal (Category 4)
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H317	Sensitisation, Skin (Category 1)
H318	Serious eye damage/eye irritation (Category 1)
H319	Serious eye damage/eye irritation (Category 2A)
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H330	Acute toxicity,inhalation (Category 1, 2)
H331	Acute toxicity,inhalation (Category 3)
H332	Acute toxicity,inhalation (Category 4)
H333	Acute toxicity,inhalation (Category 5)
H334	Sensitisation, respiratory (Category 1)
H335	Specific target organ toxicity, single exposure; Respiratory tract irritation (Category 3)
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H340	Germ cell mutagenicity (Category 1A, 1B)
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H400	Hazardous to the aquatic environment, acute hazard (Category 1)
H401	Hazardous to the aquatic environment, acute hazard (Category 2)
H402	Hazardous to the aquatic environment, acute hazard (Category 3)
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