Ethoxy-methyl-oxophosphanium
- Catalog NO.:A846721
- CAS No. : 16391-07-4
- Molecular Formula:C3H9O2P
- Molecular Weight: 108.08
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Bulk Inquiry
1. Please click the to confirm the discount and stock quantity.
2. Click“Bulk Inquiry”to ask for quotations of other quantity.
3. The price does not include shipping and bank charges.
Product Details
CAS Number | 16391-07-4 | Appearance | Colorless liquid |
Catalog Number | A846721 | MDL Number | MFCD01941125 |
Molecular Formula | C3H9O2P | Molecular Weight | 108.08 |
Boiling Point | 115.661oC at 760 mmHg | Melting Point | |
Flash Point | 36.579oC | Density | |
Synonyms | ETHYL METHYLPHOSPHINATE | ||
Storage Condition | Store in a tightly closed container,in a cool and dry place |
Safety
GHS Pictogram | |||
Signal Word | Warning | UN Number | |
Hazard Statements | Class | ||
Precautionary Statements | Packing Group |
Description
PF-670462 is a potent inhibitor of the CK1 isoforms CK1ε and CK1δ (IC50 = 7.7 and 14 nM, respectively). Inhibition of CKIepsilon yields a perturbation of oscillator function that forestalls light as a zeitgeber, and they demonstrate that pharmacological tools such as PF-670462 may yield valuable insight into clock function. Casein kinase Iepsilon (CKIepsilon) is an essential component of the biological clock, phosphorylating PER proteins, and in doing so regulating their turnover and nuclear entry in oscillator cells of the suprachiasmatic nucleus (SCN). |