2,4,6-Trivinylcyclotriboroxane pyridine complex

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For R&D use only.

Catalog NO.：A905587
CAS No. : 95010-17-6
Molecular Formula：C₁₁H₁₄B₃NO₃
Molecular Weight： 240.67

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Quality Control&SDS

SDS COA NMR

Product Details

CAS Number	95010-17-6	Appearance	Off-white powder
Catalog Number	A905587	MDL Number	MFCD03839940
Molecular Formula	C₁₁H₁₄B₃NO₃	Molecular Weight	240.67
Boiling Point	78-80 °C	Melting Point	44-52 °C
Flash Point		Density
Synonyms	2,4,6-trivinyl-1,3,5,2,4,6-trioxatriborinane compound with pyridine (1:1);TRIVINYLBOROXIN PYRIDINE COMPLEX
Storage Condition	Store in a tightly closed container,in a cool and dry place

Safety

GHS Pictogram
Signal Word	Warning	UN Number
Hazard Statements	H319	Class
Precautionary Statements	P305+P351+P338	Packing Group

Description

Sunitinib free base is an oral, small-molecule, multi-targeted receptor tyrosine kinase (RTK) inhibitor. Sunitinib malate salt was approved by the FDA for the treatment of renal cell carcinoma (RCC) and imatinib-resistant gastrointestinal stromal tumor (GIST) on January 26, 2006. Sunitinib inhibits cellular signaling by targeting multiple receptor tyrosine kinases (RTKs). The simultaneous inhibition of these targets therefore reduces tumor vascularization and triggers cancer cell apoptosis and thus results in tumor shrinkage. Sunitinib also inhibits CD117 (c-KIT), the receptor tyrosine kinase that (when improperly activated by mutation) drives the majority of gastrointestinal stromal cell tumors.

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