For R&D use only.

Methyl (2,2,2-trifluoroethyl) carbonate

  • Catalog NO.:A905391
  • CAS No. : 156783-95-8
  • Molecular Formula:C4H5F3O3
  • Molecular Weight: 158.08
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Quality Control&SDS
SDS COA NMR

Product Details

CAS Number 156783-95-8 Appearance Colorless liquid
Catalog Number A905391 MDL Number MFCD28054295
Molecular Formula C4H5F3O3 Molecular Weight 158.08
Boiling Point Melting Point
Flash Point Density
Synonyms Methyl (2,2,2-Trifluoroethyl) Carbonate
Storage Condition Store in a tightly closed container,in a cool and dry place

Safety

GHS Pictogram
Signal Word Danger UN Number 3272
Hazard Statements H302;H315;H319;H335 Class 3
Precautionary Statements P261;P305+P351+P338 Packing Group

Description

Sunitinib free base is an oral, small-molecule, multi-targeted receptor tyrosine kinase (RTK) inhibitor. Sunitinib malate salt was approved by the FDA for the treatment of renal cell carcinoma (RCC) and imatinib-resistant gastrointestinal stromal tumor (GIST) on January 26, 2006. Sunitinib inhibits cellular signaling by targeting multiple receptor tyrosine kinases (RTKs). The simultaneous inhibition of these targets therefore reduces tumor vascularization and triggers cancer cell apoptosis and thus results in tumor shrinkage. Sunitinib also inhibits CD117 (c-KIT), the receptor tyrosine kinase that (when improperly activated by mutation) drives the majority of gastrointestinal stromal cell tumors.

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Methyl (2,2,2-trifluoroethyl) carbonate
Methyl (2,2,2-Trifluoroethyl) Carbonate