2,2,3,3,4,4,4-Heptafluoro-1-butanol

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For R&D use only.

Catalog NO.：A905873
CAS No. : 375-01-9
Molecular Formula：C₄H₃F₇O
Molecular Weight： 200.06

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Product Details

CAS Number	375-01-9	Appearance
Catalog Number	A905873	MDL Number	MFCD00004674
Molecular Formula	C₄H₃F₇O	Molecular Weight	200.06
Boiling Point	95oC at 760mmHg	Melting Point
Flash Point	25oC	Density	1.534g/cm3
Synonyms	2,2,3,3,4,4,4-Heptafluoro-1-butanol
Storage Condition	Store in a tightly closed container,in a cool and dry place

Safety

GHS Pictogram
Signal Word	Warning	UN Number	UN 1987
Hazard Statements		Class	3
Precautionary Statements		Packing Group	III

Description

Sunitinib free base is an oral, small-molecule, multi-targeted receptor tyrosine kinase (RTK) inhibitor. Sunitinib malate salt was approved by the FDA for the treatment of renal cell carcinoma (RCC) and imatinib-resistant gastrointestinal stromal tumor (GIST) on January 26, 2006. Sunitinib inhibits cellular signaling by targeting multiple receptor tyrosine kinases (RTKs). The simultaneous inhibition of these targets therefore reduces tumor vascularization and triggers cancer cell apoptosis and thus results in tumor shrinkage. Sunitinib also inhibits CD117 (c-KIT), the receptor tyrosine kinase that (when improperly activated by mutation) drives the majority of gastrointestinal stromal cell tumors.

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