β-Sitosterol

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For R&D use only.

Catalog NO.：A840577
CAS No. : 83-46-5
Molecular Formula：C₂₉H₅₀O
Molecular Weight： 414.71

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Product Details

CAS Number	83-46-5	Appearance
Catalog Number	A840577	MDL Number	MFCD00003631
Molecular Formula	C₂₉H₅₀O	Molecular Weight	414.71
Boiling Point	501.9°C at 760 mmHg	Melting Point
Flash Point		Density
Synonyms	(3S,8S,9S,10R,13R,14S,17R)-17-((2R,5R)-5-ethyl-6-methylheptan-2-yl)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol
Storage Condition	Store in a tightly closed container,in a cool and dry place

Safety

GHS Pictogram
Signal Word	Danger	UN Number	1888
Hazard Statements	H302-H315-H319-H331-H336-H351-H361-H372	Class	6.1
Precautionary Statements	P201-P261-P304+P340+P312-P305+P351+P338-P308+P313-P403+P233	Packing Group	Ⅲ

Description

ABT-737 is an orally available inhibitor of the nuclear enzymes poly(ADP-ribose) polymerase (PARP) 1 and 2, with potential antineoplastic activity. Upon administration, ABT-767 selectively binds to PARP 1 and 2, thereby preventing repair of damaged DNA via the base excision repair (BER) pathway. This agent enhances the accumulation of DNA strand breaks and promotes genomic instability eventually leading to apoptosis. ABT-767 may enhance the cytotoxicity of DNA-damaging agents and reverse tumor cell chemo- and radioresistance.

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H200	Explosives (Unstable Explosive)
H201	Explosives （Div 1.1)
H202	Explosives (Div 1.2)
H203	Explosives (Div 1.3)
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H335	Specific target organ toxicity, single exposure; Respiratory tract irritation (Category 3)
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H340	Germ cell mutagenicity (Category 1A, 1B)
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H400	Hazardous to the aquatic environment, acute hazard (Category 1)
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