For R&D use only.

1alpha,25-Dihydroxyvitamin D2

  • Catalog NO.:A869040
  • CAS No. : 60133-18-8
  • Molecular Formula:C28H44O3
  • Molecular Weight: 428.65
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Quality Control&SDS
SDS COA NMR

Product Details

CAS Number 60133-18-8 Appearance White powder
Catalog Number A869040 MDL Number MFCD00869499
Molecular Formula C28H44O3 Molecular Weight 428.65
Boiling Point Melting Point
Flash Point Density
Synonyms 1alpha,25-Dihydroxycalciferol
Storage Condition Store in a tightly closed container,in a cool and dry place

Safety

GHS Pictogram
Signal Word Danger UN Number 2811
Hazard Statements H301+H311-H330-H372 Class 6.1
Precautionary Statements P260-P280-P284-P301+P310-P310 Packing Group

Description

FIPI is a potent and selective phospholipase D inhibitor. FIPI attenuate mercury-induced lipid signaling leading to protection against cytotoxicity in aortic endothelial cells. FIPI rapidly blocks in vivo PA production with subnanomolar potency. We were surprised to find that several biological processes blocked by 1-butanol are not affected by FIPI, suggesting the need for re-evaluation of proposed FIPI does inhibit PLD regulation of F-actin cytoskeleton reorganization, cell spreading, and chemotaxis, indicating potential utility for it as a therapeutic for autoimmunity and cancer metastasis.

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1alpha,25-Dihydroxyvitamin D2
1alpha,25-Dihydroxycalciferol