5,7-bis(1,1-dimethylethyl)-3-phenyl-(3H)-benzofuran-2-one

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For R&D use only.

Catalog NO.：A901832
CAS No. : 66737-86-8
Molecular Formula：C₂₂H₂₆O₂
Molecular Weight： 322.44

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Product Details

CAS Number	66737-86-8	Appearance
Catalog Number	A901832	MDL Number
Molecular Formula	C₂₂H₂₆O₂	Molecular Weight	322.44
Boiling Point		Melting Point
Flash Point		Density
Synonyms	5,7-di-tert-butyl-3-phenylbenzofuran-2(3H)-one
Storage Condition	Store in a tightly closed container,in a cool and dry place

Safety

GHS Pictogram
Signal Word	Warning	UN Number
Hazard Statements		Class
Precautionary Statements		Packing Group

Description

A 803467 is a selective Nav1.8 sodium channel blocker with an IC50 of 8 nM; over 100-fold more selective vs. human Nav1.2, 1.3, 1.5 and 1.7. IC50 value: 8 nM Target: Nav1.8 sodium channel A 803467 dose-dependently reduces behavioral responses in a variety of neuropathic and inflammatory pain models.

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