(R)-2-(1-Boc-3-pyrrolidinyl)acetic Acid
- Catalog NO.：A13707
- CAS No. : 204688-60-8
- Molecular Formula：C11H19NO4
- Molecular Weight： 229.27
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Product Details
| CAS Number | 204688-60-8 | Appearance | |
| Catalog Number | A13707 | MDL Number | MFCD05861547 |
| Molecular Formula | C11H19NO4 | Molecular Weight | 229.27 |
| Boiling Point | 357.4°C at 760 mmHg | Melting Point | |
| Flash Point | Density | ||
| Synonyms | (R)-2-(1-(tert-butoxycarbonyl)pyrrolidin-3-yl)acetic acid;(R)-(1-BOC-PYRROLIDIN-3-YL)-ACETIC ACID | ||
| Storage Condition | Store in a tightly closed container,in a cool and dry place | ||
Safety
| GHS Pictogram |
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| Signal Word | Danger | UN Number | 2811 |
| Hazard Statements | H301;H410 | Class | 6.1 |
| Precautionary Statements | P273;P301+P310;P501 | Packing Group | Ⅲ |
Description
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Talabostat, also known as PT-100, is dipeptidyl peptidase inhibitor with antineoplastic and hematopoiesis- stimulating activities. By cleaving N-terminal Xaa-Pro or Xaa-Ala residues, talabostat inhibits dipeptidyl peptidases, such as fibroblast activation protein (FAP), resulting in the stimulation of cytokine and chemokine production and specific T-cell immunity and T-cell- dependent activity. This agent may also stimulate the production of colony stimulating factors, such as granulocyte colony stimulating factor (G-CSF), resulting in the stimulation of hematopoiesis. Dipeptidyl peptidases are involved in the activation of polypeptide hormones and chemokines. |
