Ziprasidone HCl

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For R&D use only.

Catalog NO.：A890906
CAS No. : 122883-93-6
Molecular Formula：C₂₁H₂₂Cl₂N₄Os
Molecular Weight： 449.39

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Product Details

CAS Number	122883-93-6	Appearance
Catalog Number	A890906	MDL Number	MFCD06795476
Molecular Formula	C₂₁H₂₂Cl₂N₄Os	Molecular Weight	449.39
Boiling Point		Melting Point
Flash Point		Density
Synonyms	5-[2-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]ethyl]-6-chloro-1,3-dihydroindol-2-one hydrochloride
Storage Condition	Store in a tightly closed container,in a cool and dry place

Safety

GHS Pictogram
Signal Word	Warning	UN Number
Hazard Statements	H302-H315-H319-H332-H335	Class
Precautionary Statements	P261-P280-P305+P351+P338	Packing Group

Description

Ziprazidone is approved for the treatment of schizophrenia, and acute mania and mixed states associated with bipolar disorder. Its intramuscular injection form is approved for acute agitation in schizophrenic patients for whom treatment with just ziprasidone is appropriate. The mechanism of action of ziprasidone, as with other drugs having efficacy in schizophrenia, is unknown. However, it has been proposed that this drug's efficacy in schizophrenia is mediated through a combination of dopamine type 2 (D2) and serotonin type 2 (5HT2) antagonism. As with other drugs having efficacy in bipolar disorder, the mechanism of action of ziprasidone in bipolar disorder is unknown.

199191-69-0 (Mesylate Trihydrate);

122883-93-6 (HCl salt);

138982-67-9 (HCl hydrate);

146939-27-7 (free base)

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