For R&D use only.

2-Amino-6-iodobenzoic acid

  • Catalog NO.:A879430
  • CAS No. : 20776-52-7
  • Molecular Formula:C7H6InO2
  • Molecular Weight: 263.03
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Product Details

CAS Number 20776-52-7 Appearance
Catalog Number A879430 MDL Number
Molecular Formula C7H6InO2 Molecular Weight 263.03
Boiling Point 372.2°C at 760 mmHg Melting Point
Flash Point Density
Synonyms 2-Amino-6-iodobenzoic acid
Storage Condition Store in a tightly closed container,in a cool and dry place

Safety

GHS Pictogram
Signal Word Warning UN Number
Hazard Statements H302-H315-H319-H335 Class
Precautionary Statements P261-P305+P351+P338 Packing Group

Description

FIPI is a potent and selective phospholipase D inhibitor. FIPI attenuate mercury-induced lipid signaling leading to protection against cytotoxicity in aortic endothelial cells. FIPI rapidly blocks in vivo PA production with subnanomolar potency. We were surprised to find that several biological processes blocked by 1-butanol are not affected by FIPI, suggesting the need for re-evaluation of proposed FIPI does inhibit PLD regulation of F-actin cytoskeleton reorganization, cell spreading, and chemotaxis, indicating potential utility for it as a therapeutic for autoimmunity and cancer metastasis.

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2-Amino-6-iodobenzoic acid
2-Amino-6-iodobenzoic acid