For R&D use only.

2-Methoxy-4-trifluoromethylphenylboronic acid

  • Catalog NO.:A820790
  • CAS No. : 312936-89-3
  • Molecular Formula:C8H8BF3O3
  • Molecular Weight: 219.95
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Product Details

CAS Number 312936-89-3 Appearance Off-white powder
Catalog Number A820790 MDL Number MFCD03428511
Molecular Formula C8H8BF3O3 Molecular Weight 219.95
Boiling Point 309.9°C at 760 mmHg Melting Point
Flash Point Density
Synonyms [2-methoxy-4-(trifluoromethyl)phenyl]boronic acid;(2-Methoxy-4-(trifluoromethyl)phenyl)boronic acid
Storage Condition Store in a tightly closed container,in a cool and dry place

Safety

GHS Pictogram
Signal Word Warning UN Number
Hazard Statements H302-H315-H319-H332-H335 Class
Precautionary Statements P261-P280-P305+P351+P338 Packing Group

Description

BAY 87-2243 is a highly potent and selective inhibitor of hypoxia-induced gene activation, which has antitumor activities by inhibition of mitochondrial complex I. BAY 87-2243 mproves local tumor control after fractionated irradiation in a schedule-dependent manner in head and neck human xenografts. BAY-87-2243 markedly decreased nuclear HIF-1α expression and pimonidazole hypoxic fraction already after 3 days of drug treatment. BAY-87-2243 prior to RT significantly reduced TCD50 from 123 to 100 Gy (p=0.037). Additional BAY-87-2243 application during RT did not decrease TCD50.

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2-Methoxy-4-trifluoromethylphenylboronic acid
[2-methoxy-4-(trifluoromethyl)phenyl]boronic acid;(2-Methoxy-4-(trifluoromethyl)phenyl)boronic acid