3-Cyano-4-oxo-piperidine-1-carboxylic acid tert-butyl ester

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For R&D use only.

Catalog NO.：A843951
CAS No. : 914988-10-6
Molecular Formula：C₁₁H₁₆N₂O₃
Molecular Weight： 224.26

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Product Details

CAS Number	914988-10-6	Appearance
Catalog Number	A843951	MDL Number	MFCD11109814
Molecular Formula	C₁₁H₁₆N₂O₃	Molecular Weight	224.26
Boiling Point	375.1°C at 760 mmHg	Melting Point
Flash Point		Density
Synonyms	tert-Butyl 3-cyano-4-oxopiperidine-1-carboxylate
Storage Condition	Store in a tightly closed container,in a cool and dry place

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GHS Pictogram
Signal Word	Warning	UN Number
Hazard Statements	H302-H315-H319-H335	Class
Precautionary Statements	P261-P305+P351+P338	Packing Group

Description

Venetoclax, also known as ABT-199 or GDC0199, is an orally bioavailable, selective small molecule inhibitor of the anti-apoptotic protein Bcl-2, with potential antineoplastic activity. Venetoclax mimics BH3-only proteins, the native ligands of Bcl-2 and apoptosis activators, by binding to the hydrophobic groove of Bcl-2 proteins thereby repressing Bcl-2 activity and restoring apoptotic processes in tumor cells.

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H200	Explosives (Unstable Explosive)
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