Retosiban
- Catalog NO.:A857525
- CAS No. : 820957-38-8
- Molecular Formula:C27H34N4O5
- Molecular Weight: 494.25
Note*
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Bulk Inquiry
1. Please click the to confirm the discount and stock quantity.
2. Click“Bulk Inquiry”to ask for quotations of other quantity.
3. The price does not include shipping and bank charges.
Quality Control&SDS
Product Details
CAS Number | 820957-38-8 | Appearance | |
Catalog Number | A857525 | MDL Number | MFCD19443707 |
Molecular Formula | C27H34N4O5 | Molecular Weight | 494.25 |
Boiling Point | Melting Point | ||
Flash Point | Density | ||
Synonyms | (3R,6R)-6-[(2S)-butan-2-yl]-3-(2,3-dihydro-1H-inden-2-yl)-1-[(1R)-1-(2-methyl-1,3-oxazol-4-yl)-2-morpholin-4-yl-2-oxoethyl]piperazine-2,5-dione | ||
Storage Condition | Store in a tightly closed container,in a cool and dry place |
Safety
GHS Pictogram | |||
Signal Word | Warning | UN Number | |
Hazard Statements | Class | ||
Precautionary Statements | Packing Group |
Description
Retosiban, also known as GSK-221,149-A; is an oral active, potent and selective, sub-nanomolar (Ki = 0.65 nM) oxytocin receptor antagonist with >1400-fold selectivity over the related vasopressin receptors. Retosiban inhibits the procontractile effect of stretch on human myometrium. retosiban prevented stretch-induced stimulation of human myometrial contractility. Retosiban treatment is a potential approach for preventing preterm birth in multiple pregnancy. Retosiban is being developed by GlaxoSmithKline for the treatment of preterm labour. |