2-(Chloromethyl)-5-fluoropyrimidine

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For R&D use only.

Catalog NO.：A904623
CAS No. : 1196151-61-7
Molecular Formula：C₅H₄ClFN₂
Molecular Weight： 146.55

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Product Details

CAS Number	1196151-61-7	Appearance
Catalog Number	A904623	MDL Number	MFCD13189598
Molecular Formula	C₅H₄ClFN₂	Molecular Weight	146.55
Boiling Point		Melting Point
Flash Point		Density
Synonyms	2-(Chloromethyl)-5-fluoropyrimidine
Storage Condition	Store in a tightly closed container,in a cool and dry place

Safety

GHS Pictogram
Signal Word	Warning	UN Number
Hazard Statements		Class
Precautionary Statements		Packing Group

Description

Ganetespib, also known as STA-9090, is a synthetic small-molecule inhibitor of heat shock protein 90 (Hsp90) with potential antineoplastic activity. Hsp90 inhibitor STA-9090 binds to and inhibits Hsp90, resulting in the proteasomal degradation of oncogenic client proteins, the inhibition of cell proliferation and the elevation of heat shock protein 72 (Hsp72); it may inhibit the activity of multiple kinases, such as c-Kit, EGFR, and Bcr-Abl, which as client proteins depend on functional HsP90 for maintenance.

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