4,4,5,5-Tetramethyl-2-(4-phenoxyphenyl)-1,3,2-dioxaborolane

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For R&D use only.

Catalog NO.：A5279
CAS No. : 269410-26-6
Molecular Formula：C₁₈H₂₁O₃B
Molecular Weight： 296.17

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Quality Control&SDS

SDS COA NMR

Product Details

CAS Number	269410-26-6	Appearance	Off-white solid
Catalog Number	A5279	MDL Number	MFCD06795691
Molecular Formula	C₁₈H₂₁O₃B	Molecular Weight	296.17
Boiling Point	393.2±25.0℃ at 760 mmHg	Melting Point
Flash Point		Density
Synonyms	4,4,5,5-Tetramethyl-2-(4-phenoxyphenyl)-1,3,2-dioxaborolane;4-Phenoxyphenylboronic Acid Pinacol Ester
Storage Condition	Store in a tightly closed container,in a cool and dry place

Safety

GHS Pictogram
Signal Word	Warning	UN Number
Hazard Statements	H302-H315-H319-H335	Class
Precautionary Statements	P261-P305+P351+P338	Packing Group

Description

AT-7519 is an orally bioavailable small molecule CDK inhibitor with potential antineoplastic activity. AT7519M selectively binds to and inhibits cyclin dependent kinases (CDKs), which may result in cell cycle arrest, induction of apoptosis, and inhibition of tumor cell proliferation. CDKs are serine/theronine kinases involved in regulation of the cell cycle and may be overexpressed in some types of cancer cells.

902135-91-5 (HCl)

844442-38-2 (free base)

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H200	Explosives (Unstable Explosive)
H201	Explosives （Div 1.1)
H202	Explosives (Div 1.2)
H203	Explosives (Div 1.3)
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H300	Acute toxicity,oral (Category 1, 2)
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H302	Acute toxicity,oral (Category 4)
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H400	Hazardous to the aquatic environment, acute hazard (Category 1)
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