For R&D use only.

Bis(2-cyanoethyl) N,N-DiisopropylphosphoraMidite

  • Catalog NO.:A855597
  • CAS No. : 102690-88-0
  • Molecular Formula:C12H22N3O2P
  • Molecular Weight: 271.30
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Product Details

CAS Number 102690-88-0 Appearance Light yellow liquid
Catalog Number A855597 MDL Number MFCD00797597
Molecular Formula C12H22N3O2P Molecular Weight 271.30
Boiling Point Melting Point
Flash Point Density
Synonyms Bis(2-cyanoethyl) diisopropylphosphoramidite
Storage Condition Store in a tightly closed container,in a cool and dry place

Safety

GHS Pictogram
Signal Word Danger UN Number 2810
Hazard Statements H301+H311+H331-H315-H319 Class 6.1
Precautionary Statements P261-P280-P301+P310-P305+P351+P338-P311 Packing Group

Description

Alpelisib, also known as BLY719, is an orally bioavailable phosphatidylinositol 3-kinase (PI3K) inhibitor with potential antineoplastic activity. PI3K inhibitor BYL719 specifically inhibits PIK3 in the PI3K/AKT kinase (or protein kinase B) signaling pathway, thereby inhibiting the activation of the PI3K signaling pathway. This may result in inhibition of tumor cell growth and survival in susceptible tumor cell populations. Activation of the PI3K signaling pathway is frequently associated with tumorigenesis. Dysregulated PI3K signaling may contribute to tumor resistance to a variety of antineoplastic agents. Check for active clinical trials or closed clinical trials using this agent.

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Bis(2-cyanoethyl) N,N-DiisopropylphosphoraMidite
Bis(2-cyanoethyl) diisopropylphosphoramidite