5'-DMT-2'-TBDMS-ibu-rG

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For R&D use only.

Catalog NO.：A852152
CAS No. : 81279-39-2
Molecular Formula：C₄₁H₅₁N₅O₈Si
Molecular Weight： 769.96

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SDS COA NMR

Product Details

CAS Number	81279-39-2	Appearance	yellow crystal
Catalog Number	A852152	MDL Number	Not available
Molecular Formula	C₄₁H₅₁N₅O₈Si	Molecular Weight	769.96
Boiling Point		Melting Point
Flash Point		Density
Synonyms	5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-2'-O-[(tert-butyl)dimethylsilyl]-N-(2-methyl-1-oxopropyl)guanosine;5'-O-DMT-2'-O-iBu-N-Bz-Guanosine
Storage Condition	Store in a tightly closed container,in a cool and dry place

Safety

GHS Pictogram
Signal Word	Warning	UN Number
Hazard Statements	H302-H315-H319-H332-H335	Class
Precautionary Statements	P261-P280-P305+P351+P338	Packing Group

Description

Talabostat, also known as PT-100, is dipeptidyl peptidase inhibitor with antineoplastic and hematopoiesis- stimulating activities. By cleaving N-terminal Xaa-Pro or Xaa-Ala residues, talabostat inhibits dipeptidyl peptidases, such as fibroblast activation protein (FAP), resulting in the stimulation of cytokine and chemokine production and specific T-cell immunity and T-cell- dependent activity. This agent may also stimulate the production of colony stimulating factors, such as granulocyte colony stimulating factor (G-CSF), resulting in the stimulation of hematopoiesis. Dipeptidyl peptidases are involved in the activation of polypeptide hormones and chemokines.

150080-09-4 (mesylate)

149682-77-9 (free base)

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