I-BRD9

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For R&D use only.

Catalog NO.：A901788
CAS No. : 1714146-59-4
Molecular Formula：C₂₂H₂₂F₃N₃O₃S₂
Molecular Weight： 497.55

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Product Details

CAS Number	1714146-59-4	Appearance	White powder
Catalog Number	A901788	MDL Number
Molecular Formula	C₂₂H₂₂F₃N₃O₃S₂	Molecular Weight	497.55
Boiling Point		Melting Point
Flash Point		Density
Synonyms	N-(1,1-Dioxidotetrahydro-2H-thiopyran-4-yl)-5-ethyl-4-oxo-7-(3-(trifluoromethyl)phenyl)-4,5-dihydrothieno[3,2-c]pyridine-2-carboximidamide
Storage Condition	Store in a tightly closed container,in a cool and dry place

Safety

GHS Pictogram
Signal Word	Danger	UN Number	2811
Hazard Statements	H301	Class	6.1
Precautionary Statements	P301+P310	Packing Group	Ⅲ

Description

Talabostat, also known as PT-100, is dipeptidyl peptidase inhibitor with antineoplastic and hematopoiesis- stimulating activities. By cleaving N-terminal Xaa-Pro or Xaa-Ala residues, talabostat inhibits dipeptidyl peptidases, such as fibroblast activation protein (FAP), resulting in the stimulation of cytokine and chemokine production and specific T-cell immunity and T-cell- dependent activity. This agent may also stimulate the production of colony stimulating factors, such as granulocyte colony stimulating factor (G-CSF), resulting in the stimulation of hematopoiesis. Dipeptidyl peptidases are involved in the activation of polypeptide hormones and chemokines.

150080-09-4 (mesylate)

149682-77-9 (free base)

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