For R&D use only.

tert-butyl 6-amino-2-azaspiro[3.3]heptane-2-carboxylate

  • Catalog NO.:A804678
  • CAS No. : 1211586-09-2
  • Molecular Formula:C11H20N2O2
  • Molecular Weight: 212.29
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Quality Control&SDS
SDS COA NMR

Product Details

CAS Number 1211586-09-2 Appearance White solid
Catalog Number A804678 MDL Number MFCD15071432
Molecular Formula C11H20N2O2 Molecular Weight 212.29
Boiling Point Melting Point
Flash Point Density
Synonyms tert-butyl 2-amino-6-azaspiro[3.3]heptane-6-carboxylate
Storage Condition Store in a tightly closed container,in a cool and dry place

Safety

GHS Pictogram
Signal Word Warning UN Number
Hazard Statements H302-H315-H319-H332-H335 Class
Precautionary Statements P261-P280-P305+P351+P338 Packing Group

Description

FIPI is a potent and selective phospholipase D inhibitor. FIPI attenuate mercury-induced lipid signaling leading to protection against cytotoxicity in aortic endothelial cells. FIPI rapidly blocks in vivo PA production with subnanomolar potency. We were surprised to find that several biological processes blocked by 1-butanol are not affected by FIPI, suggesting the need for re-evaluation of proposed FIPI does inhibit PLD regulation of F-actin cytoskeleton reorganization, cell spreading, and chemotaxis, indicating potential utility for it as a therapeutic for autoimmunity and cancer metastasis.

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tert-butyl 6-amino-2-azaspiro[3.3]heptane-2-carboxylate
tert-butyl 2-amino-6-azaspiro[3.3]heptane-6-carboxylate