4,4'-Di-tert-butyl-2,2'-bipyridine

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For R&D use only.

Catalog NO.：A846200
CAS No. : 72914-19-3
Molecular Formula：C₁₈H₂₄N₂
Molecular Weight： 268.40

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Product Details

CAS Number	72914-19-3	Appearance
Catalog Number	A846200	MDL Number	MFCD01863731
Molecular Formula	C₁₈H₂₄N₂	Molecular Weight	268.40
Boiling Point	395.4°C at 760 mmHg	Melting Point	159-161oC(lit.)
Flash Point	150.2oC	Density	0.977g/cm3
Synonyms	4,4'-Di-tert-butyl-2,2'-bipyridine
Storage Condition	Store in a tightly closed container,in a cool and dry place

Safety

GHS Pictogram
Signal Word	Warning	UN Number
Hazard Statements	H315-H319-H335	Class
Precautionary Statements	P261-P305+P351+P338	Packing Group

Description

Tavaborole, also known as AN-2690 (trade name Kerydin) is a topical antifungal medication for the treatment of onychomycosis, a fungal infection of the nail and nail bed. Tavaborole began its Phase 3 trials in December 2010 and was approved in July 2014. Tavaborole inhibits an essential fungal enzyme, Leucyl-tRNA synthetase, or LeuRS, required for protein synthesis. The inhibition of protein synthesis leads to termination of cell growth and cell death, eliminating the fungal infection. No treatment-related systemic side effects were observed in any of its clinical trials.

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P309 + P311	IF exposed or if you feel unwell: call a POISON CENTER or doctor/physician.
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P370 + P378	In case of fire: Use … for extinction.
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P401	Store …
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P411 + P235	Store at temperatures not exceeding … oC/…oF. Keep cool.

P501	Dispose of contents/container to..…
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H200	Explosives (Unstable Explosive)
H201	Explosives （Div 1.1)
H202	Explosives (Div 1.2)
H203	Explosives (Div 1.3)
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H300	Acute toxicity,oral (Category 1, 2)
H301	Acute toxicity,oral (Category 3)
H302	Acute toxicity,oral (Category 4)
H303	Acute toxicity,oral (Category 5)
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H318	Serious eye damage/eye irritation (Category 1)
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H400	Hazardous to the aquatic environment, acute hazard (Category 1)
H401	Hazardous to the aquatic environment, acute hazard (Category 2)
H402	Hazardous to the aquatic environment, acute hazard (Category 3)
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