For R&D use only.

Flomoxef

  • Catalog NO.:A846063
  • CAS No. : 99665-00-6
  • Molecular Formula:C15H18F2N6O7S2
  • Molecular Weight: 496.46
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Product Details

CAS Number 99665-00-6 Appearance White to off-white powder
Catalog Number A846063 MDL Number
Molecular Formula C15H18F2N6O7S2 Molecular Weight 496.46
Boiling Point 232-233 °C(lit.) Melting Point 29-31 °C(lit.)
Flash Point >230 °F Density 1.85 g/cm3
Synonyms (6R,7R)-7-[[2-(difluoromethylsulfanyl)acetyl]amino]-3-[[1-(2-hydroxyethyl)tetrazol-5-yl]sulfanylmethyl]-7-methoxy-8-oxo-5-oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Storage Condition Store in a tightly closed container,in a cool and dry place

Safety

GHS Pictogram
Signal Word Warning UN Number
Hazard Statements H302;H315;H319;H335 Class
Precautionary Statements P261;P305+P351+P338 Packing Group

Description

Potent and selective autotaxin inhibitor (IC50 = 28 nM). Binds and inhibits autotaxin reversibly. Displays no activity against the proteasome, recombinant NPP1 or alkaline phosphatase. Inhibits ATX-mediated cell migration in an A2058 melanoma cell assay.

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Flomoxef
(6R,7R)-7-[[2-(difluoromethylsulfanyl)acetyl]amino]-3-[[1-(2-hydroxyethyl)tetrazol-5-yl]sulfanylmethyl]-7-methoxy-8-oxo-5-oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid