1H-Indazole-6-boronicacid

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For R&D use only.

Catalog NO.：A10552
CAS No. : 885068-10-0
Molecular Formula：C₇H₇N₂O₂B
Molecular Weight： 161.95

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Product Details

CAS Number	885068-10-0	Appearance
Catalog Number	A10552	MDL Number	MFCD04972419
Molecular Formula	C₇H₇N₂O₂B	Molecular Weight	161.95
Boiling Point		Melting Point
Flash Point		Density
Synonyms	1H-indazol-6-ylboronic acid;1H-Indazole-6-boronic Acid
Storage Condition	Store in a tightly closed container,in a cool and dry place

Safety

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Signal Word	Warning	UN Number
Hazard Statements		Class
Precautionary Statements		Packing Group

Description

ABT-737 is an orally available inhibitor of the nuclear enzymes poly(ADP-ribose) polymerase (PARP) 1 and 2, with potential antineoplastic activity. Upon administration, ABT-767 selectively binds to PARP 1 and 2, thereby preventing repair of damaged DNA via the base excision repair (BER) pathway. This agent enhances the accumulation of DNA strand breaks and promotes genomic instability eventually leading to apoptosis. ABT-767 may enhance the cytotoxicity of DNA-damaging agents and reverse tumor cell chemo- and radioresistance.

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H200	Explosives (Unstable Explosive)
H201	Explosives （Div 1.1)
H202	Explosives (Div 1.2)
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H300	Acute toxicity,oral (Category 1, 2)
H301	Acute toxicity,oral (Category 3)
H302	Acute toxicity,oral (Category 4)
H303	Acute toxicity,oral (Category 5)
H304	Aspiration hazard (Category 1)
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H317	Sensitisation, Skin (Category 1)
H318	Serious eye damage/eye irritation (Category 1)
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H330	Acute toxicity,inhalation (Category 1, 2)
H331	Acute toxicity,inhalation (Category 3)
H332	Acute toxicity,inhalation (Category 4)
H333	Acute toxicity,inhalation (Category 5)
H334	Sensitisation, respiratory (Category 1)
H335	Specific target organ toxicity, single exposure; Respiratory tract irritation (Category 3)
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H340	Germ cell mutagenicity (Category 1A, 1B)
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H400	Hazardous to the aquatic environment, acute hazard (Category 1)
H401	Hazardous to the aquatic environment, acute hazard (Category 2)
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H420	Hazardous to the ozone layer (Category 1)