ML224

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For R&D use only.

Catalog NO.：A902430
CAS No. : 1338824-21-7
Molecular Formula：C₃₁H₃₁N₃O₅
Molecular Weight： 525.59

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SDS COA NMR

Product Details

CAS Number	1338824-21-7	Appearance	White powder
Catalog Number	A902430	MDL Number
Molecular Formula	C₃₁H₃₁N₃O₅	Molecular Weight	525.59
Boiling Point		Melting Point
Flash Point		Density
Synonyms	N-(4-((5-(3-(furan-2-ylmethyl)-4-oxo-1,2,3,4-tetrahydroquinazolin-2-yl)-2-methoxybenzyl)oxy)-3,5-dimethylphenyl)acetamide;ML224
Storage Condition	Store in a tightly closed container,in a cool and dry place

Safety

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Hazard Statements		Class
Precautionary Statements		Packing Group

Description

CZC24832 is the first selective inhibitor of phosphoinositide 3-kinase γ (PI3Kγ) with efficacy in in vitro and in vivo models of inflammation. Extensive target- and cell-based profiling of CZC24832 revealed regulation of interleukin-17-producing T helper cell (T(H)17) differentiation by PI3Kγ, thus reinforcing selective inhibition of PI3Kγ as a potential treatment for inflammatory and autoimmune diseases.

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H200	Explosives (Unstable Explosive)
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H400	Hazardous to the aquatic environment, acute hazard (Category 1)
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