H-Met(O)-OH
- Catalog NO.:A821216
- CAS No. : 3226-65-1
- Molecular Formula:C5H11NO3S
- Molecular Weight: 165.21
Note*
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Bulk Inquiry
1. Please click the to confirm the discount and stock quantity.
2. Click“Bulk Inquiry”to ask for quotations of other quantity.
3. The price does not include shipping and bank charges.
Quality Control&SDS
COA
Product Details
CAS Number | 3226-65-1 | Appearance | |
Catalog Number | A821216 | MDL Number | MFCD00063093 |
Molecular Formula | C5H11NO3S | Molecular Weight | 165.21 |
Boiling Point | 434.3°C at 760 mmHg | Melting Point | |
Flash Point | Density | ||
Synonyms | (2S)-2-amino-4-methylsulfinyl-butanoic acid | ||
Storage Condition | Store in a tightly closed container,in a cool and dry place |
Safety
GHS Pictogram | |||
Signal Word | Warning | UN Number | |
Hazard Statements | H315-H319-H335 | Class | |
Precautionary Statements | P261-P305+P351+P338 | Packing Group |
Description
Entinostat, also known as MS-275 or SNDX-275, is a potent HDAC inhibitor with potential antineoplastic activity. Entinostat binds to and inhibits histone deacetylase, an enzyme that regulates chromatin structure and gene transcription. This agent appears to exert dose-dependent effects in human leukemia cells including cyclin-dependent kinase inhibitor 1A (p21/CIP1/WAF1)-dependent growth arrest and differentiation at low drug concentrations; a marked induction of reactive oxygen species (ROS); mitochondrial damage; caspase activation; and, at higher concentrations, apoptosis. |