1-Methyl-1H-pyrazolo[3,4-b]pyridin-5-amine

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For R&D use only.

Catalog NO.：A892678
CAS No. : 1190380-60-9
Molecular Formula：C₇H₈N₄
Molecular Weight： 148.17

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Product Details

CAS Number	1190380-60-9	Appearance
Catalog Number	A892678	MDL Number	MFCD17016021
Molecular Formula	C₇H₈N₄	Molecular Weight	148.17
Boiling Point		Melting Point
Flash Point		Density
Synonyms	1-Methyl-1H-pyrazolo[3,4-b]pyridin-5-amine
Storage Condition	Store in a tightly closed container,in a cool and dry place

Safety

GHS Pictogram
Signal Word	Warning	UN Number
Hazard Statements		Class
Precautionary Statements		Packing Group

Description

Epalrestat is an aldose reductase inhibitor that is currently available for the treatment of diabetic neuropathy. In vivo, Epalrestat treatment significantly ameliorated the bleomycin-mediated histological fibrosis alterations and blocked collagen deposition concomitantly with reversing bleomycin-induced expression up-regulation of TGF-β1, AR, α-SMA and collagen I (both mRNA and protein).

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H200	Explosives (Unstable Explosive)
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H302	Acute toxicity,oral (Category 4)
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H304	Aspiration hazard (Category 1)
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H317	Sensitisation, Skin (Category 1)
H318	Serious eye damage/eye irritation (Category 1)
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H330	Acute toxicity,inhalation (Category 1, 2)
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H400	Hazardous to the aquatic environment, acute hazard (Category 1)
H401	Hazardous to the aquatic environment, acute hazard (Category 2)
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