JNJ-26854165
- Catalog NO.:A862315
- CAS No. : 881202-45-5
- Molecular Formula:C21H20N4
- Molecular Weight: 328.41
Note*
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3. The price does not include shipping and bank charges.
Bulk Inquiry
1. Please click the to confirm the discount and stock quantity.
2. Click“Bulk Inquiry”to ask for quotations of other quantity.
3. The price does not include shipping and bank charges.
Quality Control&SDS
SDS
Product Details
CAS Number | 881202-45-5 | Appearance | Off-white solid |
Catalog Number | A862315 | MDL Number | MFCD16620518 |
Molecular Formula | C21H20N4 | Molecular Weight | 328.41 |
Boiling Point | Melting Point | ||
Flash Point | Density | ||
Synonyms | JNJ 26854165;N1-(2-(1H-indol-3-yl)ethyl)-N4-(pyridin-4-yl)benzene-1,4-diamine;JNJ-26854165 | ||
Storage Condition | Store in a tightly closed container,in a cool and dry place |
Safety
GHS Pictogram | |||
Signal Word | Warning | UN Number | |
Hazard Statements | H302-H315-H319-H335 | Class | |
Precautionary Statements | P261-P305+P351+P338 | Packing Group |
Description
Serdemetan, also known as JNJ-26854165, is an orally bioavailable, small-molecule HDM2 antagonist with potential antineoplastic activity. HDM2 antagonist JNJ-26854165 inhibits the binding of the HDM2–p53 complex to the proteasome, blocking the degradation of p53; p53 signaling and p53-mediated induction of tumor cell apoptosis may thus be restored. In addition to p53, degradation of other HDM2 client proteins may be inhibited. |