Protoporphyrin IX dimethyl ester

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For R&D use only.

Catalog NO.：A870251
CAS No. : 5522-66-7
Molecular Formula：C₃₆H₃₈N₄O₄
Molecular Weight： 590.71

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Product Details

CAS Number	5522-66-7	Appearance	Magenta powder
Catalog Number	A870251	MDL Number	MFCD29073939
Molecular Formula	C₃₆H₃₈N₄O₄	Molecular Weight	590.71
Boiling Point	1016.967°C at 760 mmHg	Melting Point
Flash Point		Density
Synonyms	Dimethyl 8,13-divinyl-3,7,12,17-tetramethyl-21H,23H-porphine-2,18-dipropionate
Storage Condition	Store in a tightly closed container,in a cool and dry place

Safety

GHS Pictogram
Signal Word	Warning	UN Number
Hazard Statements	H302-H315-H319-H335	Class
Precautionary Statements	P261-P305+P351+P338	Packing Group

Description

ABT-737 is an orally available inhibitor of the nuclear enzymes poly(ADP-ribose) polymerase (PARP) 1 and 2, with potential antineoplastic activity. Upon administration, ABT-767 selectively binds to PARP 1 and 2, thereby preventing repair of damaged DNA via the base excision repair (BER) pathway. This agent enhances the accumulation of DNA strand breaks and promotes genomic instability eventually leading to apoptosis. ABT-767 may enhance the cytotoxicity of DNA-damaging agents and reverse tumor cell chemo- and radioresistance.

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H200	Explosives (Unstable Explosive)
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