4-(Difluoromethoxy)phenol
- Catalog NO.:A842368
- CAS No. : 87789-47-7
- Molecular Formula:C7H6F2O2
- Molecular Weight: 160.12
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Product Details
CAS Number | 87789-47-7 | Appearance | Colorless liquid |
Catalog Number | A842368 | MDL Number | MFCD00236236 |
Molecular Formula | C7H6F2O2 | Molecular Weight | 160.12 |
Boiling Point | 225.2°C at 760 mmHg | Melting Point | |
Flash Point | Density | ||
Synonyms | 4-(difluoromethoxy)phenol | ||
Storage Condition | Store in a tightly closed container,in a cool and dry place |
Safety
GHS Pictogram | |||
Signal Word | Warning | UN Number | |
Hazard Statements | H302-H315-H319-H335 | Class | |
Precautionary Statements | P261-P305+P351+P338 | Packing Group |
Description
Cabozantinib, also known as XL-184 or BMS-907351, is an orally bioavailable, small molecule receptor tyrosine kinase (RTK) inhibitor with potential antineoplastic activity. Cabozantinib strongly binds to and inhibits several tyrosine receptor kinases. Specifically, cabozantinib appears to have a strong affinity for the hepatocyte growth factor receptor (Met) and vascular endothelial growth factor receptor 2 (VEGFR2), which may result in inhibition of tumor growth and angiogenesis, and tumor regression. Cabozantinib was approved by the U.S. FDA in November 2012 for the treatment of medullary thyroid cancer. |