2-(4-Chlorophenyl)-3-(trifluoroMethyl)pyrazole-4-carboxylic acid

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For R&D use only.

Catalog NO.：A845871
CAS No. : 98534-80-6
Molecular Formula：C₁₁H₆ClF₃N₂O₂
Molecular Weight： 290.63

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Product Details

CAS Number	98534-80-6	Appearance
Catalog Number	A845871	MDL Number	MFCD00068142
Molecular Formula	C₁₁H₆ClF₃N₂O₂	Molecular Weight	290.63
Boiling Point		Melting Point
Flash Point		Density
Synonyms	1-(4-chlorophenyl)-5-(trifluoromethyl)pyrazole-4-carboxylic acid
Storage Condition	Store in a tightly closed container,in a cool and dry place

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Description

ABT-737 is an orally available inhibitor of the nuclear enzymes poly(ADP-ribose) polymerase (PARP) 1 and 2, with potential antineoplastic activity. Upon administration, ABT-767 selectively binds to PARP 1 and 2, thereby preventing repair of damaged DNA via the base excision repair (BER) pathway. This agent enhances the accumulation of DNA strand breaks and promotes genomic instability eventually leading to apoptosis. ABT-767 may enhance the cytotoxicity of DNA-damaging agents and reverse tumor cell chemo- and radioresistance.

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H200	Explosives (Unstable Explosive)
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