6-Chloro-2-methylnicotinonitrile

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For R&D use only.

Catalog NO.：A9000
CAS No. : 66909-36-2
Molecular Formula：C₇H₅ClN₂
Molecular Weight： 152.58

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Product Details

CAS Number	66909-36-2	Appearance
Catalog Number	A9000	MDL Number	MFCD07082897
Molecular Formula	C₇H₅ClN₂	Molecular Weight	152.58
Boiling Point	246.462°C at 760 mmHg	Melting Point
Flash Point		Density
Synonyms	6-chloro-3-isocyano-2-methylpyridine
Storage Condition	Store in a tightly closed container,in a cool and dry place

Safety

GHS Pictogram
Signal Word	Warning	UN Number
Hazard Statements	H302	Class
Precautionary Statements	P280-P305+P351+P338	Packing Group

Description

Ipatasertib, also known as GDC-0068, is an orally bioavailable inhibitor of the serine/threonine protein kinase Akt (protein kinase B) with potential antineoplastic activity. Akt inhibitor GDC-0068 binds to and inhibits the activity of Akt in a non-ATP-competitive manner, which may result in the inhibition of the PI3K/Akt signaling pathway and tumor cell proliferation and the induction of tumor cell apoptosis.

1001264-89-6 (free base)

1489263-16-2 (HCl)

1396257-94-5 (2HCl)

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P401	Store …
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H200	Explosives (Unstable Explosive)
H201	Explosives （Div 1.1)
H202	Explosives (Div 1.2)
H203	Explosives (Div 1.3)
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H301	Acute toxicity,oral (Category 3)
H302	Acute toxicity,oral (Category 4)
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H304	Aspiration hazard (Category 1)
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H318	Serious eye damage/eye irritation (Category 1)
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H330	Acute toxicity,inhalation (Category 1, 2)
H331	Acute toxicity,inhalation (Category 3)
H332	Acute toxicity,inhalation (Category 4)
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H334	Sensitisation, respiratory (Category 1)
H335	Specific target organ toxicity, single exposure; Respiratory tract irritation (Category 3)
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H371	Specific target organ toxicity, single exposure (Category 2)
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H373	Specific target organ toxicity, repeated exposure (Category 2)

H400	Hazardous to the aquatic environment, acute hazard (Category 1)
H401	Hazardous to the aquatic environment, acute hazard (Category 2)
H402	Hazardous to the aquatic environment, acute hazard (Category 3)
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