IKK-16 hydrochloride
- Catalog NO.:A893077
- CAS No. : 1186195-62-9
- Molecular Formula:C28H31ClN6Os
- Molecular Weight: 520.09
Note*
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Bulk Inquiry
1. Please click the to confirm the discount and stock quantity.
2. Click“Bulk Inquiry”to ask for quotations of other quantity.
3. The price does not include shipping and bank charges.
Product Details
CAS Number | 1186195-62-9 | Appearance | White powder |
Catalog Number | A893077 | MDL Number | MFCD09971091 |
Molecular Formula | C28H31ClN6Os | Molecular Weight | 520.09 |
Boiling Point | Melting Point | ||
Flash Point | Density | ||
Synonyms | N-(4-Pyrrolidin-1-yl-piperidin-1-yl)-[4-(4-benzo[b]thiophen-2-yl-pyrimidin-2-ylamino)phenyl]carboxamidehydrochloride | ||
Storage Condition | Store in a tightly closed container,in a cool and dry place |
Safety
GHS Pictogram | |||
Signal Word | Warning | UN Number | |
Hazard Statements | H302;H315;H319;H335 | Class | |
Precautionary Statements | P261;P305+P351+P338 | Packing Group |
Description
IKK-16 is a potent and slective inhibitor of IκB kinase (IKK) (IC50 values are 40, 70 and 200 nM for IKKβ, IKK complex and IKKα respectively). KK-16 inhibits TNFα-stimulated expression of the adhesion molecules E-selectin, ICAM-1, and VCAM-1 in HUVEC cells. |