4-(4-Amino-2-trifluoromethyl-benzyl)-piperazine-1-carboxylic acid tert-butyl ester

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Catalog NO.：A10263
CAS No. : 859027-30-8
Molecular Formula：C₁₇H₂₄F₃N₃O₂
Molecular Weight： 359.39

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Quality Control&SDS

SDS COA NMR

Product Details

CAS Number	859027-30-8	Appearance	White powder
Catalog Number	A10263	MDL Number	MFCD11519259
Molecular Formula	C₁₇H₂₄F₃N₃O₂	Molecular Weight	359.39
Boiling Point		Melting Point
Flash Point		Density
Synonyms	tert-butyl 4-(4-amino-2-(trifluoromethyl)benzyl)piperazine-1-carboxylate
Storage Condition	Store in a tightly closed container,in a cool and dry place

Safety

GHS Pictogram
Signal Word	Warning	UN Number
Hazard Statements	H302;H315;H319;H335	Class
Precautionary Statements	P261;P305+P351+P338	Packing Group

Description

Palonosetron (INN, trade name Aloxi) is a 5-HT3 antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). It is used for the control of delayed CINVÂ—nausea and vomiting and there are tentative data to suggest that it may be better than granisetron. Palonosetron is administered intravenously, as a single dose, 30 minutes before chemotherapy, or as a single oral capsule one hour before chemotherapy. The oral formulation was approved on August 22, 2008 for prevention of acute CINV alone, as a large clinical trial did not show oral administration to be as effective as intravenous use against delayed CINV.

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H200	Explosives (Unstable Explosive)
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