tert-Butyl 2-(piperidin-4-yl)acetate

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For R&D use only.

Catalog NO.：A812529
CAS No. : 180182-07-4
Molecular Formula：C₁₁H₂₁NO₂
Molecular Weight： 199.29

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Quality Control&SDS

SDS COA NMR

Product Details

CAS Number	180182-07-4	Appearance	Yellow liquid
Catalog Number	A812529	MDL Number	MFCD06738957
Molecular Formula	C₁₁H₂₁NO₂	Molecular Weight	199.29
Boiling Point	259°C at 760 mmHg	Melting Point
Flash Point		Density
Synonyms	tert-Butyl 2-(piperidin-4-yl)acetate
Storage Condition	Store in a tightly closed container,in a cool and dry place

Safety

GHS Pictogram
Signal Word	Warning	UN Number
Hazard Statements	H314-H318	Class
Precautionary Statements	P280-P305+P351+P338-P310	Packing Group

Description

Mertansine refers to the thiol-containing maytansinoid, DM1 (N2’-deacetyl-N2’-(3-mercapto-1-oxopropyl)maytansine) attached to a monoclonal antibody through reaction of the thiol group with the SPP (N-succinimidyl 4-(2-pyridyldithio)) linker to create an antibody-drug conjugate or ADC. Experimental ADCs with the SPP-DM1 design include lorvotuzumab mertansine. DM1 can also be linked to an antibody using the SMCC (4-(3-mercapto-2,5-dioxo-1-pyrrolidinylmethyl)-cylohexanecarboxylic acid) linker, in which case the International Nonproprietary Name of the conjugate formed contains the word emtansine. DM1 and its attachment via these linkers result from ImmunoGen Inc research. Trastuzumab emtansine (T-DM1) is an anti-HER2/neu antibody-drug conjugate.

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H200	Explosives (Unstable Explosive)
H201	Explosives （Div 1.1)
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H301	Acute toxicity,oral (Category 3)
H302	Acute toxicity,oral (Category 4)
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