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Methyl 5-bromo-1H-pyrrole-3-carboxylate

  • Catalog NO.:A857729
  • CAS No. : 16420-39-6
  • Molecular Formula:C6H6BrNO2
  • Molecular Weight: 204.02
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Product Details

CAS Number 16420-39-6 Appearance
Catalog Number A857729 MDL Number MFCD09841652
Molecular Formula C6H6BrNO2 Molecular Weight 204.02
Boiling Point Melting Point
Flash Point 160.148℃ Density
Synonyms methyl 5-bromo-1H-pyrrole-3-carboxylate
Storage Condition Store in a tightly closed container,in a cool and dry place


GHS Pictogram
Signal Word Warning UN Number
Hazard Statements H315-H319-H335 Class
Precautionary Statements P261-P305+P351+P338 Packing Group


PF-670462 is a potent inhibitor of the CK1 isoforms CK1ε and CK1δ (IC50 = 7.7 and 14 nM, respectively). Inhibition of CKIepsilon yields a perturbation of oscillator function that forestalls light as a zeitgeber, and they demonstrate that pharmacological tools such as PF-670462 may yield valuable insight into clock function. Casein kinase Iepsilon (CKIepsilon) is an essential component of the biological clock, phosphorylating PER proteins, and in doing so regulating their turnover and nuclear entry in oscillator cells of the suprachiasmatic nucleus (SCN).

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Methyl 5-bromo-1H-pyrrole-3-carboxylate
methyl 5-bromo-1H-pyrrole-3-carboxylate