3-Nonene-2-one

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Catalog NO.：A904004
CAS No. : 18402-83-0
Molecular Formula：C₉H₁₆O
Molecular Weight： 140.22

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Product Details

CAS Number	18402-83-0	Appearance
Catalog Number	A904004	MDL Number	MFCD00010241
Molecular Formula	C₉H₁₆O	Molecular Weight	140.22
Boiling Point	182°C at 20 mmHg	Melting Point
Flash Point		Density
Synonyms	(E)-Non-3-en-2-one
Storage Condition	Store in a tightly closed container,in a cool and dry place

Safety

GHS Pictogram
Signal Word	Warning	UN Number
Hazard Statements	H302-H315-H319-H335	Class
Precautionary Statements	P261-P305+P351+P338	Packing Group

Description

Ponatinib, also known as AP24534 is an oral drug for the treatment of chronic myeloid leukemia (CML) and Philadelphia chromosome–positive (Ph+) acute lymphoblastic leukemia (ALL). It is a multi-targeted tyrosine-kinase inhibitor. Some forms of CML, those that have the T315I mutation, are resistant to current therapies such as imatinib. Ponatinib has been designed to be effective against these types of tumors. Ponatinib was approved in 2012.

943319-70-8 (free base)

1114544-31-8 (HCl)

1232836-25-7 (tris-hydrochloride)

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P370 + P378	In case of fire: Use … for extinction.
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H200	Explosives (Unstable Explosive)
H201	Explosives （Div 1.1)
H202	Explosives (Div 1.2)
H203	Explosives (Div 1.3)
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H300	Acute toxicity,oral (Category 1, 2)
H301	Acute toxicity,oral (Category 3)
H302	Acute toxicity,oral (Category 4)
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H314	Skin corrosion/irritation (Category 1A, B, C)
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H318	Serious eye damage/eye irritation (Category 1)
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H330	Acute toxicity,inhalation (Category 1, 2)
H331	Acute toxicity,inhalation (Category 3)
H332	Acute toxicity,inhalation (Category 4)
H333	Acute toxicity,inhalation (Category 5)
H334	Sensitisation, respiratory (Category 1)
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H340	Germ cell mutagenicity (Category 1A, 1B)
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H371	Specific target organ toxicity, single exposure (Category 2)
H372	Specific target organ toxicity, repeated exposure (Category 1)
H373	Specific target organ toxicity, repeated exposure (Category 2)

H400	Hazardous to the aquatic environment, acute hazard (Category 1)
H401	Hazardous to the aquatic environment, acute hazard (Category 2)
H402	Hazardous to the aquatic environment, acute hazard (Category 3)
H410	Hazardous to the aquatic environment, long-term hazard(Category 1)
H411	Hazardous to the aquatic environment, long-term hazard (Category 2)
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