For R&D use only.

3-Chloro-2-fluorobenzaldehyde

  • Catalog NO.:A21250
  • CAS No. : 85070-48-0
  • Molecular Formula:C7H4ClFO
  • Molecular Weight: 158.56
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Product Details

CAS Number 85070-48-0 Appearance Light yellow liquid or crystallize
Catalog Number A21250 MDL Number MFCD01631571
Molecular Formula C7H4ClFO Molecular Weight 158.56
Boiling Point 214 °C(lit.) Melting Point 26-27°C
Flash Point 186 °F Density 1.35
Synonyms 3-Chloro-2-fluoro-benzaldehyde
Storage Condition Store in a tightly closed container,in a cool and dry place

Safety

GHS Pictogram
Signal Word Warning UN Number Not hazmat
Hazard Statements H227; H315; H319; H335 Class
Precautionary Statements P210; P261; P264; P271; P280; P302+P352; P304+P340; P305+P351+P338; P312; P321; P332+P313; P337+P313; P362; P370+P378; P403+P233; P403+P235; P405; P501 Packing Group

Description

Ruxolitinib, also known as INC424 and INCB18424 or INCB018424, is an orally bioavailable Janus-associated kinase (JAK) inhibitor with potential antineoplastic and immunomodulating activities. Ruxolitinib specifically binds to and inhibits protein tyrosine kinases JAK 1 and 2, which may lead to a reduction in inflammation and an inhibition of cellular proliferation. The JAK-STAT (signal transducer and activator of transcription) pathway plays a key role in the signaling of many cytokines and growth factors and is involved in cellular proliferation, growth, hematopoiesis, and the immune response; JAK kinases may be upregulated in inflammatory diseases, myeloproliferative disorders, and various malignancies.

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3-Chloro-2-fluorobenzaldehyde
3-Chloro-2-fluoro-benzaldehyde