6-bromo-3-(1-methylpyrazol-4-yl)-5-[(3S)-piperidin-3-yl]pyrazolo[1,5-a]pyrimidin-7-amine

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Catalog NO.：A903422
CAS No. : 891494-64-7
Molecular Formula：C₁₅H₁₈BrN₇
Molecular Weight： 376.25

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Product Details

CAS Number	891494-64-7	Appearance
Catalog Number	A903422	MDL Number	MFCD23135227
Molecular Formula	C₁₅H₁₈BrN₇	Molecular Weight	376.25
Boiling Point		Melting Point
Flash Point		Density
Synonyms	6-bromo-3-(1-methylpyrazol-4-yl)-5-[(3S)-piperidin-3-yl]pyrazolo[1,5-a]pyrimidin-7-amine
Storage Condition	Store in a tightly closed container,in a cool and dry place

Safety

GHS Pictogram
Signal Word	Warning	UN Number
Hazard Statements	H302-H315-H319-H335	Class
Precautionary Statements	P261-P305+P351+P338	Packing Group

Description

SCH900776, also known as MK-8776. is an agent targeting cell cycle checkpoint kinase 1 (Chk1) with potential radiosensitization and chemosensitization activities. Chk1 inhibitor SCH 900776 specifically binds to and inhibits Chk1, which may result in tumor cells bypassing Chk1-dependent cell cycle arrest in the S and G2/M phases to undergo DNA repair prior to entry into mitosis; tumor cells may thus be sensitized to the DNA-damaging effects of ionizing radiation and alkylating chemotherapeutic agents.

Related CAS #: 891494-63-6

891494-64-7 (S-isomer)

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