For R&D use only.

Troxacitabine

  • Catalog NO.:A846759
  • CAS No. : 145918-75-8
  • Molecular Formula:C8H11N3O4
  • Molecular Weight: 213.19
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Quality Control&SDS
SDS COA LC-MS/GC-MS NMR

Product Details

CAS Number 145918-75-8 Appearance White powder
Catalog Number A846759 MDL Number MFCD00871100
Molecular Formula C8H11N3O4 Molecular Weight 213.19
Boiling Point 422.5°C at 760 mmHg Melting Point
Flash Point Density
Synonyms 4-amino-1-((2S,4S)-2-(hydroxymethyl)-1,3-dioxolan-4-yl)pyrimidin-2(1H)-one
Storage Condition Store in a tightly closed container,in a cool and dry place

Safety

GHS Pictogram
Signal Word Warning UN Number
Hazard Statements H302-H315-H319-H332-H335 Class
Precautionary Statements P261-P280-P305+P351+P338 Packing Group

Description

Epalrestat is an aldose reductase inhibitor that is currently available for the treatment of diabetic neuropathy. In vivo, Epalrestat treatment significantly ameliorated the bleomycin-mediated histological fibrosis alterations and blocked collagen deposition concomitantly with reversing bleomycin-induced expression up-regulation of TGF-β1, AR, α-SMA and collagen I (both mRNA and protein).

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Troxacitabine
4-amino-1-((2S,4S)-2-(hydroxymethyl)-1,3-dioxolan-4-yl)pyrimidin-2(1H)-one