Bardoxolone Methyl
- Catalog NO.:A847580
- CAS No. : 218600-53-4
- Molecular Formula:C32H43NO4
- Molecular Weight: 505.69
Note*
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Bulk Inquiry
1. Please click the to confirm the discount and stock quantity.
2. Click“Bulk Inquiry”to ask for quotations of other quantity.
3. The price does not include shipping and bank charges.
Product Details
CAS Number | 218600-53-4 | Appearance | White powder |
Catalog Number | A847580 | MDL Number | MFCD11983137 |
Molecular Formula | C32H43NO4 | Molecular Weight | 505.69 |
Boiling Point | 600.8°C at 760 mmHg | Melting Point | |
Flash Point | Density | ||
Synonyms | NSC 713200; RTA 402;;CDDO Methyl ester; CDDOMe; NSC 713200; RTA 402; RTA-402; RTA402;(4aS,6aR,6bS,8aR,12aS,14bS)-Methyl 11-cyano-2,2,6a,6b,9,9,12a-he | ||
Storage Condition | Store in a tightly closed container,in a cool and dry place |
Safety
GHS Pictogram | |||
Signal Word | Warning | UN Number | |
Hazard Statements | H302-H315-H319-H332-H335 | Class | |
Precautionary Statements | P261-P280-P305+P351+P338 | Packing Group |
Description
Bardoxolone methyl (also known as “RTA 402” and “CDDO-methyl ester”) is an orally-available first-in-class synthetic triterpenoid belonging to the antioxidant inflammation modulator (AIM) class. It is the most potent known inducer of the Nrf2 pathway to enter clinical development and works to suppress both oxidative stress and inflammation. Bardoxolone methyl is currently being developed by Reata Pharmaceuticals, Inc. in partnership with Abbott Laboratories and Kyowa Hakko Kirin, for the treatment of advanced chronic kidney disease (CKD) in type 2 diabetes mellitus patients. |