1,2-O-(1-methylethylidene)-4-C- [(phenylmethoxy)methyl]-3-O- (phenylmethyl)-L-Lyxofuranose
- Catalog NO.：A848360
- CAS No. : 153186-10-8
- Molecular Formula：C23H28O6
- Molecular Weight： 400.46
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|CAS Number||153186-10-8||Appearance||Off-White powder|
|Catalog Number||A848360||MDL Number||MFCD20269093|
|Molecular Formula||C23H28O6||Molecular Weight||400.46|
|Boiling Point||Melting Point|
|Storage Condition||Store in a tightly closed container,in a cool and dry place|
|Signal Word||Warning||UN Number|
|Precautionary Statements||P261;P305+P351+P338||Packing Group|
Mibefradil, also known as Ro 405967 or Ro 40-5967, is a drug for the treatment of hypertension and chronic angina pectoris. It belongs to a group known as calcium channel blockers. The mechanism of action of mibefradil is characterized by the selective blockade of transient, low-voltage-activated (T-type) calcium channels over long-lasting, high-voltage-activated (L-type) calcium channels, which is probably responsible for many of its unique properties. It is nonselective. On June 8, 1998, Roche announced the voluntary withdrawal of the drug from the market, one year after approval by the FDA, due to the potential for drug interactions, some of them deadly, which may occur when it is taken together with some other medications.