For R&D use only.

NXY-059

  • Catalog NO.:A25442
  • CAS No. : 168021-79-2
  • Molecular Formula:C11H13NNa2O7S2
  • Molecular Weight: 381.33
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Product Details

CAS Number 168021-79-2 Appearance White solid
Catalog Number A25442 MDL Number MFCD09833648
Molecular Formula C11H13NNa2O7S2 Molecular Weight 381.33
Boiling Point Melting Point
Flash Point Density
Synonyms 1,3-Benzenedisulfonic acid, 4-[(Z)-[(1,1-dimethylethyl)oxidoazanylidene]methyl]-, sodium salt
Storage Condition Store in a tightly closed container,in a cool and dry place

Safety

GHS Pictogram
Signal Word Warning UN Number
Hazard Statements H302-H315-H319-H335 Class
Precautionary Statements P261-P305+P351+P338 Packing Group

Description

Disufenton sodium, also known as Cerovive, OKN007, NXY-059, is a disulfonyl derivative of phenyl-tert-butyl nitrone (PBN), with potential anti-glioma activity. Although the exact mechanism(s) of action of OKN007 are still largely unknown, this agent appears to inhibit cancer cell proliferation and migration. This agent appears to inhibit the activity of sulfatase 2 (SULF2), a highly specific endoglucosamine-6-sulfatase that is overexpressed in the extracellular matrix of cancer cells and catalyzes the removal of sulfate from the 6-O-sulfate esters of heparin.

168021-79-2 (sodium)

168021-77-0 (free acid)

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NXY-059
1,3-Benzenedisulfonic acid, 4-[(Z)-[(1,1-dimethylethyl)oxidoazanylidene]methyl]-, sodium salt