Apatinib mesylate

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For R&D use only.

Catalog NO.：A899008
CAS No. : 1218779-75-9
Molecular Formula：C₂₅H₂₇N₅O₄S
Molecular Weight： 493.58

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Quality Control&SDS

SDS COA NMR

Product Details

CAS Number	1218779-75-9	Appearance	White powder
Catalog Number	A899008	MDL Number	MFCD22420814
Molecular Formula	C₂₅H₂₇N₅O₄S	Molecular Weight	493.58
Boiling Point		Melting Point
Flash Point		Density
Synonyms	N-[4-(1-Cyanocyclopentyl)phenyl]-2-[(4-pyridinylmethyl)amino]-3-pyridinecarboxamide methanesulfonate
Storage Condition	Store in a tightly closed container,in a cool and dry place

Safety

GHS Pictogram
Signal Word	Warning	UN Number
Hazard Statements	H302-H315-H319-H335	Class
Precautionary Statements	P261-P305+P351+P338	Packing Group

Description

Apatinib, also known as Rivoceranib, is an orally bioavailable, small-molecule receptor tyrosine kinase inhibitor with potential antiangiogenic and antineoplastic activities. The free-base form is also known as Rivoceranib. Apatinib selectively binds to and inhibits vascular endothelial growth factor receptor 2, which may inhibit VEGF-stimulated endothelial cell migration and proliferation and decrease tumor microvessel density. In addition, this agent mildly inhibits c-Kit and c-SRC tyrosine kinases.

1218779-75-9 (mesylate)

811803-05-1 (free base)

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