CNX-774
- Catalog NO.:A892283
- CAS No. : 1202759-32-7
- Molecular Formula:C26H22FN7O3
- Molecular Weight: 499.50
Note*
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Bulk Inquiry
1. Please click the to confirm the discount and stock quantity.
2. Click“Bulk Inquiry”to ask for quotations of other quantity.
3. The price does not include shipping and bank charges.
Quality Control&SDS
SDS
Product Details
CAS Number | 1202759-32-7 | Appearance | Crystalline solid |
Catalog Number | A892283 | MDL Number | MFCD26405992 |
Molecular Formula | C26H22FN7O3 | Molecular Weight | 499.50 |
Boiling Point | Melting Point | ||
Flash Point | Density | ||
Synonyms | 4-(4-((4-((3-acrylamidophenyl)amino)-5-fluoropyrimidin-2-yl)amino)phenoxy)-N-methylpicolinamide | ||
Storage Condition | Store in a tightly closed container,in a cool and dry place |
Safety
GHS Pictogram | |||
Signal Word | Warning | UN Number | |
Hazard Statements | H302-H315-H319-H335 | Class | |
Precautionary Statements | P261-P305+P351+P338 | Packing Group |
Description
CNX-774 is a potent Btk inhibitor (IC50 < 1 nM). Recently Bruton's tyrosine kinase (BTK) , a crucial terminal kinase enzyme in the B-cell antigen receptor (BCR) signaling pathway, has emerged as an attractive target for therapeutic intervention in human malignancies and autoimmune disorders. |