Tazarotenic acid

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For R&D use only.

Catalog NO.：A803905
CAS No. : 118292-41-4
Molecular Formula：C₁₉H₁₇NO₂S
Molecular Weight： 323.40878

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Product Details

CAS Number	118292-41-4	Appearance
Catalog Number	A803905	MDL Number	MFCD00872121
Molecular Formula	C₁₉H₁₇NO₂S	Molecular Weight	323.40878
Boiling Point		Melting Point
Flash Point		Density
Synonyms	6-((4,4-dimethylthiochroman-6-yl)ethynyl)nicotinic acid;6-[2-(4,4-dimethylthiochroman-6-yl)ethynyl]pyridine-3-carboxylic acid;AGN-190299
Storage Condition	Store in a tightly closed container,in a cool and dry place

Safety

GHS Pictogram
Signal Word	Warning	UN Number
Hazard Statements		Class
Precautionary Statements		Packing Group

Description

Tazarotene is a retinoid prodrug which is converted to its active form, the cognate carboxylic acid of tazarotene (AGN 190299), by rapid deesterification in animals and man. AGN 190299 (“tazarotenic acid”) binds to all three members of the retinoic acid receptor (RAR) family: RARα, RARβ, and RARγ but shows relative selectivity for RARβ, and RARγ and may modify gene expression. The clinical significance of these findings is unknown.

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