Lapatinib ditosylate monohydrate

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For R&D use only.

Catalog NO.：A25216
CAS No. : 388082-78-8
Molecular Formula：C₄₃H₄₄ClFN₄O₁₁S₃
Molecular Weight： 943.48

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Quality Control&SDS

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Product Details

CAS Number	388082-78-8	Appearance	Yellow powder
Catalog Number	A25216	MDL Number	MFCD18904381
Molecular Formula	C₄₃H₄₄ClFN₄O₁₁S₃	Molecular Weight	943.48
Boiling Point		Melting Point
Flash Point		Density
Synonyms	N-(3-Chloro-4-((3-fluorophenyl)methoxy)phenyl)-6-(5-(((2-(methylsulfonyl)ethyl)amino)methyl)-2-furanyl)-4-quinazolinamine bis(4-methylbenzenesulfonate);Lapatinib ditosylate hydrate
Storage Condition	Store in a tightly closed container,in a cool and dry place

Safety

GHS Pictogram
Signal Word	Warning	UN Number
Hazard Statements	H302-H315-H319-H335	Class
Precautionary Statements	P261-P305+P351+P338	Packing Group

Description

Lapatinib is a synthetic, orally-active quinazoline with potential antineoplastic activity. Lapatinib reversibly blocks phosphorylation of the epidermal growth factor receptor (EGFR), ErbB2, and the Erk-1 and-2 and AKT kinases; it also inhibits cyclin D protein levels in human tumor cell lines and xenografts. EGFR and ErbB2 have been implicated in the growth of various tumor types. Check for active clinical trials or closed clinical trials using this agent.

388082-77-7 (ditosylate)

231277-92-2 (free base)

388082-78-8（ditosylate monohydrate）

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