ZM 323881 hydrochloride
- Catalog NO.:A857954
- CAS No. : 193000-39-4
- Molecular Formula:C22H19ClFN3O2
- Molecular Weight: 411.86
Note*
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Bulk Inquiry
1. Please click the to confirm the discount and stock quantity.
2. Click“Bulk Inquiry”to ask for quotations of other quantity.
3. The price does not include shipping and bank charges.
Product Details
CAS Number | 193000-39-4 | Appearance | Light yellow green solid powder |
Catalog Number | A857954 | MDL Number | MFCD08703130 |
Molecular Formula | C22H19ClFN3O2 | Molecular Weight | 411.86 |
Boiling Point | Melting Point | ||
Flash Point | Density | ||
Synonyms | 5-((7-(Benzyloxy)quinazolin-4-yl)amino)-4-fluoro-2-methylphenol hydrochloride | ||
Storage Condition | Store in a tightly closed container,in a cool and dry place |
Safety
GHS Pictogram | |||
Signal Word | Warning | UN Number | |
Hazard Statements | H302-H315-H319-H335 | Class | |
Precautionary Statements | P261-P305+P351+P338 | Packing Group |
Description
ZM323881 is a potent and selective inhibitor of VEGF-R2 tyrosine kinase in vitro (IC(50) < 2 nM), compared with other receptor tyrosine kinases, including VEGF-R1 (IC(50) > 50 microM). ZM323881 inhibits VEGF-A-induced endothelial cell proliferation (IC(50) = 8 nM) and VEGF-R2 tyrosine phosphorylation in vitro. |