For R&D use only.

Brivanib alaninate

  • Catalog NO.:A20636
  • CAS No. : 649735-63-7
  • Molecular Formula:C22H24FN5O4
  • Molecular Weight: 441.46
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Quality Control&SDS
SDS COA NMR

Product Details

CAS Number 649735-63-7 Appearance White powder
Catalog Number A20636 MDL Number MFCD22577162
Molecular Formula C22H24FN5O4 Molecular Weight 441.46
Boiling Point Melting Point
Flash Point Density
Synonyms BMS-582664;(S)-(R)-1-((4-((4-fluoro-2-methyl-1H-indol-5-yl)oxy)-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yl)oxy)propan-2-yl 2-aminopropanoate
Storage Condition Store in a tightly closed container,in a cool and dry place

Safety

GHS Pictogram
Signal Word Danger UN Number 2811
Hazard Statements H302-H360 Class 6.1
Precautionary Statements P201-P308+P313 Packing Group

Description

Brivanib is the hydrolyzed form of Brivanib alaninate, which is a vascular endothelial growth factor receptor 2 (VEGFR2) inhibitor with potential antineoplastic activity. Brivanib strongly binds to and inhibits VEGFR2, a tyrosine kinase receptor expressed almost exclusively on vascular endothelial cells; inhibition of VEGFR2 may result in inhibition of tumor angiogenesis, inhibition of tumor cell growth, and tumor regression.

649735-46-6

649735-63-7(alaninate)

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Brivanib alaninate
BMS-582664;(S)-(R)-1-((4-((4-fluoro-2-methyl-1H-indol-5-yl)oxy)-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yl)oxy)propan-2-yl 2-aminopropanoate