ML 347
- Catalog NO.:A895842
- CAS No. : 1062368-49-3
- Molecular Formula:C22H16N4O
- Molecular Weight: 352.39
Note*
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Bulk Inquiry
1. Please click the to confirm the discount and stock quantity.
2. Click“Bulk Inquiry”to ask for quotations of other quantity.
3. The price does not include shipping and bank charges.
Quality Control&SDS
Product Details
CAS Number | 1062368-49-3 | Appearance | |
Catalog Number | A895842 | MDL Number | MFCD28099805 |
Molecular Formula | C22H16N4O | Molecular Weight | 352.39 |
Boiling Point | Melting Point | ||
Flash Point | Density | ||
Synonyms | 5-[6-(4-Methoxyphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]quinoline | ||
Storage Condition | Store in a tightly closed container,in a cool and dry place |
Safety
GHS Pictogram | |||
Signal Word | Danger | UN Number | 3077 |
Hazard Statements | H302-H410 | Class | 9 |
Precautionary Statements | P264-P270-P273-P301+P312 | Packing Group | Ⅲ |
Description
Potent and selective ALK2 and ALK1 inhibitor (IC50 values are 32 and 46 nM, respectively); displays >200 fold selectivity over ALK3 and ALK6 and >400 fold selectivity over VEGF2. Exhibits no activity at ALK4, ALK5 or in a panel of related kinases. Inhibits BMP4 signaling in a functional assay (IC50 = 152 nM). |